- Basic information
- CohesinDB ID: CDBP00414969
- Locus: chr21-23452578-23453740
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000DZP, ENCSR000EAC, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE93080, GSE76893, GSE101921, GSE152721, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE38395, GSE111913, GSE155324, GSE38411, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: RH4, GM10847, GM2610, SLK, GM19240, HSPC, Liver, HuCC-T1, H9-hESC, GM2630, THP-1, Ishikawa, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, GM18526, H1-hESC, SNYDER, Lymphoblast, GM12878, GM2588, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, HeLa-Tet-On, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, HUVEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 32% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.433
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
26% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 84%,
"9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MEF2B, SMC1A, EBF1, ZBTB48, SMAD3, STAT1, FOXA1, SRF, HOXB13, ERG, YY1, CTCFL, RAD21, HIF1A, ATF2, GATA3, GABPA, PAX5, PRDM14, HAND2, ARNTL, TRIM28, CREB1, KDM5B, ESR1, CTCF, BCL11A, AR, FLI1, NOTCH3, JUND, TCF3, FOXP1, SMC3, STAG1, RBPJ
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 19
- Related genes and loops