- Basic information
- CohesinDB ID: CDBP00414999
- Locus: chr21-23693948-23695132
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Data sourse: ENCSR000BLD, GSE72082, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000BKV, GSE138405, GSE152721, ENCSR198ZYJ, GSE138105, ENCSR703TNG, ENCSR000EHW, ENCSR000ECE, GSE62063, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR000EDE, GSE126990, ENCSR000ECS, GSE131577
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HL-60, Neurons-H1, SLK, THP-1, Ramos, HeLa-S3, SK-N-SH, K-562, OCI-AML-3, HAP1, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: NIPBL,SA1,Rad21,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 93%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MAFG, GATA2, FOXA2, MAX, PIAS1, RAD21, STAG2, FLI1, ESR1, MAFF, FOXA1, FOXP1, SRF, PHOX2B, SMC3, CTCF, MAFK, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops
- Related gene:
- Related loop:
chr21:21000000-21025000~~chr21:23675000-23700000,
chr21:22075000-22100000~~chr21:23700000-23725000,
chr21:23100000-23125000~~chr21:23700000-23725000,
chr21:23125000-23150000~~chr21:23700000-23725000,
chr21:23150000-23175000~~chr21:23700000-23725000,
chr21:23250000-23275000~~chr21:23700000-23725000,
chr21:23400000-23425000~~chr21:23675000-23700000,
chr21:23400000-23425000~~chr21:23700000-23725000,
chr21:23475000-23500000~~chr21:23700000-23725000,
chr21:23575000-23600000~~chr21:23700000-23725000,
chr21:23700000-23725000~~chr21:23825000-23850000,
chr21:23700000-23725000~~chr21:24675000-24700000,
chr21:23700000-23725000~~chr21:25300000-25325000,