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Basic information

CohesinDB ID: CDBP00415000

Locus: chr21-23725511-23726204

Data sourse: ENCSR000BLD, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE25021, GSE108869, ENCSR000BTU, GSE93080, ENCSR000EAC, GSE138405, GSE152721, GSE116344, GSE145327, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR167MTG, GSE129526, ENCSR000EDE, GSE68388, GSE126990, GSE50893

Cell type: RH4, GM10847, GM2610, HuCC-T1, H9-hESC, GM2630, Ishikawa, GM12890, HeLa-S3, GM2255, GM18486, GM18526, H1-hESC, GM18951, SNYDER, GM12878, GM2588, SK-N-SH, GM19239, GM19193, GM19099, HUES64, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, GM19238, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 11% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.678

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 28% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 84%, "9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, TOP2A, XBP1, FOXA1, ZNF654, SRF, MEF2C, RELA, EZH1, RAD21, PRDM1, GRHL3, HIF1A, SMC3, ESR1, CTCF, ZNF786, AR, REST, GATA2, HSF1, SMC1, TEAD4, STAG1

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00415000