- Basic information
- CohesinDB ID: CDBP00415025
- Locus: chr21-23853603-23854355
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, GSE116868, ENCSR000EGW, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE101921, GSE152721, GSE120943, ENCSR198ZYJ, GSE138105, GSE130135, ENCSR703TNG, GSE145327, GSE94872, ENCSR000EEG, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, GSE62063, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE131956, GSE129526, ENCSR000HPG, GSE155324, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, GM10847, GM2610, SLK, GM19240, Liver, TC-32, HuCC-T1, H9-hESC, GM2630, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, HUVEC, Ramos, GM19238, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 30% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.433
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
29% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 86%,
"9_Het": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMC1A, CBX1, NKX2-2, STAG2, FOXA1, ZFP37, SRF, ZNF654, MEF2C, CDK9, TRIM22, HOXB13, RELA, ZBTB2, MYC, ARID1B, CTCFL, PRDM1, RAD21, HIF1A, CBFA2T3, NKX3-1, SUPT5H, GATA1, ZNF143, NFE2, DACH1, PDX1, TRIM28, PIAS1, SMAD1, KDM5B, ESR1, GRHL2, CTCF, BCL11A, KLF1, TBX21, AR, ARID2, REST, GATA2, IRF4, BRD4, SMC1, SMC3, ZNF24, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
- Related loop:
chr21:17775000-17800000~~chr21:23825000-23850000,
chr21:23225000-23250000~~chr21:23825000-23850000,
chr21:23275000-23300000~~chr21:23825000-23850000,
chr21:23700000-23725000~~chr21:23825000-23850000,
chr21:23725000-23750000~~chr21:23825000-23850000,
chr21:23825000-23850000~~chr21:24075000-24100000,
chr21:23850000-23875000~~chr21:23950000-23975000,
chr21:23850000-23875000~~chr21:24500000-24525000,
chr21:23850000-23875000~~chr21:25300000-25325000,
chr21:23853101-23855059~~chr21:23967784-23969703,
chr21:23853126-23855655~~chr21:23967674-23970175,
chr21:23853126-23855655~~chr21:24513395-24515016,
chr21:23853141-23855184~~chr21:23967552-23970117,
chr21:23853150-23855185~~chr21:23967090-23970155,
chr21:23853165-23855136~~chr21:23967703-23969775,
chr21:23853200-23855526~~chr21:23967713-23970278,
chr21:23853226-23854721~~chr21:23968041-23969577,
chr21:23853333-23855128~~chr21:23967836-23970190,
chr21:23853384-23854703~~chr21:23967950-23969661,
chr21:23853400-23854672~~chr21:23967763-23970160,
chr21:23853410-23854705~~chr21:23968015-23969702,