- Basic information
- CohesinDB ID: CDBP00415039
- Locus: chr21-23936118-23936833
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE67783, GSE101921, GSE152721, GSE120943, ENCSR198ZYJ, GSE138105, ENCSR703TNG, GSE116344, GSE145327, GSE94872, GSE98367, ENCSR000EHW, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, GSE131956, GSE129526, ENCSR000HPG, GSE155324, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, HSPC, Liver, TC-32, HuCC-T1, H9-hESC, GM2630, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, Macrophage, MCF-7, THP-1, Hela-Kyoto, HCT-116, HL-60, Hep-G2, MCF-10A, Neurons-H1, HUVEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 23% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.467
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
29% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 86%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, SMC1A, FOXA2, CBX3, ZFX, TEAD4, GTF2B, WT1, ZBTB48, ZSCAN5A, FOXA1, DUX4, SRF, PBX2, SMARCC1, HOXC5, ERG, RELA, ZBTB2, CREBBP, MYC, SMARCA4, CHAMP1, RAD21, SP140, ARNT, HIF1A, XRCC5, SPIB, ZNF143, IKZF1, MITF, HAND2, TEAD1, TRIM28, KMT2A, ETV1, PIAS1, SMAD1, KDM5B, LMO2, ESR1, PHOX2B, CTCF, USF1, SPI1, AR, REST, GATA2, EGLN2, HSF1, NOTCH3, BRD4, SMC1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops