- Basic information
- CohesinDB ID: CDBP00415043
- Locus: chr21-23954122-23955363
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Data sourse: GSE62063, GSE67783, GSE86191
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Cell type: HCT-116, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
29% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, POU2F2, MEF2B, BCL6, CEBPA, RUNX1T1, MEIS2, FOXA1, CDK9, PBX2, ERG, CREBBP, PBX1, ZNF184, TCF4, GRHL3, PBX4, GATA3, TAL1, PAX5, SPIB, SUPT5H, NR3C1, STAT5B, MYB, KMT2A, ZNF26, LMO2, EVI1, SETDB1, JUN, TCF12, SPI1, BCL11A, AR, GATA2, IRF4, HSF1, BRD4, TCF3, FOXP1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 23
- Related genes and loops