- Basic information
- CohesinDB ID: CDBP00415068
- Locus: chr21-24113352-24113776
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Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR000BLY, GSE103477, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, GSE115250, GSE138405, GSE76893, GSE101921, GSE135093, GSE120943, ENCSR703TNG, GSE145327, GSE98367, ENCSR000EHW, GSE85526, ENCSR000EHX, GSE97394, ENCSR000HPG, ENCSR000EDE, GSE50893, ENCSR000ECS
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Cell type: MDM, Liver, TC-32, H9-hESC, HEKn, Ishikawa, HeLa-S3, IMR-90, GM18526, H1-hESC, Monocytes, GM12878, SK-N-SH, GM19239, Macrophage, HUES64, MCF-7, Hela-Kyoto, MCF-10A, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.778
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
20% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 87%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, MYCN, POU5F1, NME2, STAT1, FOXA1, SRF, CDK9, ZNF596, ERG, CTCFL, RAD21, ZNF444, GATA3, SMARCE1, MAFB, NR3C1, TEAD1, PIAS1, KDM5B, ESR1, CTCF, BRD2, HSF1, BRD4, JUND, SMC1, SMC3, ZZZ3, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops