- Basic information
- CohesinDB ID: CDBP00415084
- Locus: chr21-24271944-24273595
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Data sourse: GSE67783, ENCSR879KXD, ShirahigeLab-NatGen2015, ENCSR153HNT, GSE73207
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Cell type: K-562, TF-1, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 71%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, ZNF496, HMGN3, MEIS2, NME2, FOXA1, SUZ12, PBX2, LYL1, ATF3, NFIC, PRDM1, ATF4, MECOM, SMARCE1, PAX5, MITF, HDAC3, SFPQ, JMJD1C, TRIM28, E2F5, MCM7, ETV1, NFE2L2, LMO2, PITX3, HDAC8, USF2, ZFP91, CTCF, TCF12, JUN, EP300, E4F1, KLF1, MNT, GATA6, PYGO2, DPF2, E2F6, TRIM24, SOX6, CREB3, DDX20, E2F1, TEAD4, ZNF175, GATAD2A, EHMT2, POU5F1, MYCN, TOP2A, ID3, CTBP1, MTA2, ASH1L, DUX4, STAT1, HINFP, NONO, NBN, ARID3A, PHB2, HNF4G, ERG, OGG1, SMARCC2, EZH1, MYC, SMARCA4, EOMES, ARID1B, GRHL3, FOXK2, GABPA, ZNF197, XRCC5, IKZF1, LEF1, RCOR1, ZNF639, NFE2, NR2F6, TEAD2, NR3C1, CEBPB, KMT2A, CREB1, ZBTB11, TBL1XR1, NFE2L1, SPI1, HES1, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, ZNF766, EP400, ATF1, CC2D1A, RUNX1, GTF2A2, SMC1A, MAFG, HDAC1, LDB1, CEBPA, ZMIZ1, TWIST1, ZBTB2, BRD9, ZNF184, ARNT, NRF1, ELK1, TFDP1, BACH1, ZEB2, NFYA, FOXM1, CBFA2T3, ETV6, NR2C1, CDK8, SMARCB1, FOS, ZNF584, GMEB1, DIDO1, PML, MYB, CEBPD, SMAD1, VEZF1, TAF7, C11orf30, L3MBTL2, NCOA1, EVI1, STAT5A, KLF16, MAFK, BCL11A, NR4A1, REST, ZBTB7A, CCNT2, ATF7, HNRNPLL, AFF1, BCOR, TCF3, MBD2, ILK, MLLT1, PTTG1, NFATC3, CBFA2T2, KLF13, FOXA2, MTA3, RBBP5, BRF2, CBX3, CREM, MAFF, ZBTB33, ZKSCAN1, KDM1A, CREB3L1, ZNF589, RELA, TARDBP, YY1, NEUROD1, ZNF148, JUNB, CHAMP1, ZNF282, SKIL, GATA3, MGA, TAL1, MAX, ZNF740, SPIB, GATA1, MTA1, ZNF592, GFI1B, NR2F2, ZKSCAN8, ZNF83, NR2F1, TCF7L2, PKNOX1, BHLHE40, AR, PTRF, TAF1, ZBTB40, EGR1, HSF1, NCOR1, RNF2, JUND, ILF3, MYNN, MAZ, IRF9, MEF2D, ZNF24, ZNF395, ZNF316
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 30
- Related genes and loops