- Basic information
- CohesinDB ID: CDBP00415117
- Locus: chr21-24513842-24514686
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, ENCSR760NPX, ENCSR000EGW, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE101921, GSE135093, GSE152721, GSE51234, ENCSR198ZYJ, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE138105, GSE145327, ENCSR895JMI, ENCSR000EEG, GSE76815, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR807WAC, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE62063, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE38395, GSE131956, GSE110061, GSE129526, ENCSR000HPG, GSE155324, ENCSR335RKQ, ENCSR000EDE, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, GM2610, SLK, GM19240, Liver, GP5d, TC-32, B-cell, H9-hESC, GM2630, RPE, Fibroblast, THP-1, Ishikawa, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, K-562, GM18486, DKO, H1-hESC, SNYDER, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, HAP1, Macrophage, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 34% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.411
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 94%,
"9_Het": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, FOXA2, NKX2-2, ZNF660, MEIS1, MYCN, GTF2B, STAT1, FOXA1, SRF, ZNF654, CDK9, TBP, ERG, HOXC5, ZBTB2, JUNB, NEUROD1, MYC, RAD21, OTX2, GABPA, STAT3, PAX5, NKX3-1, SUPT5H, CDK8, MED1, PDX1, PIAS1, SMAD1, STAG1, ESR1, CTCF, JUN, BCL11A, SPI1, AR, PAX8, REST, GATA2, IRF4, POU2F3, BRD4, FOXP1, SMC1, SMC3, STAG2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:21000000-21025000~~chr21:24500000-24525000,
chr21:23400000-23425000~~chr21:24500000-24525000,
chr21:23850000-23875000~~chr21:24500000-24525000,
chr21:23853126-23855655~~chr21:24513395-24515016,
chr21:23967674-23970175~~chr21:24513395-24515016,
chr21:24112958-24114272~~chr21:24513419-24515155,
chr21:24374433-24376255~~chr21:24513242-24515218,
chr21:24374647-24377813~~chr21:24513418-24515189,
chr21:24374750-24375936~~chr21:24513478-24515130,
chr21:24375000-24400000~~chr21:24500000-24525000,
chr21:24376201-24377625~~chr21:24513279-24515208,
chr21:24376285-24377492~~chr21:24513242-24515218,
chr21:24418157-24419502~~chr21:24513242-24515218,
chr21:24500000-24525000~~chr21:25300000-25325000,
chr21:24513423-24515010~~chr21:25384975-25387237,
chr21:24513697-24514874~~chr21:25385247-25387032,