- Basic information
- CohesinDB ID: CDBP00415151
- Locus: chr21-24899096-24899536
-
Data sourse: GSE105004, GSE93080, GSE98367, GSE206145, GSE120943, GSE50893
-
Cell type: Macrophage, Monocytes, GM19240, GM12878, GM2588, HeLa, GM18486, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SMC3,Rad21,SA1,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 88%,
"9_Het": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, CBX5, PGR, NME2, XBP1, HNF1A, FOXA1, HDGF, PRDM1, MAF, TRIM28, BCLAF1, ESR1, MLL, OCA2, CTCF, TCF12, EP300, GATA6, TRIM24, IRF4, SMC1, TEAD4, PDX1, TFAP2C, POU2F2, CHD8, POU5F1, TOP2A, ID3, MTA2, SRF, MLLT3, NBN, ERG, HOXC5, NFKB2, MYC, RAD21, GABPA, IKZF1, TERF2, CEBPB, EBF3, SPI1, GATA2, FLI1, SMARCA5, RELB, SMC1A, CEBPA, POU4F2, ZNF654, TRIM22, SMARCC1, ZBTB2, ZNF384, NOTCH1, CREBBP, ARNT, CDK8, MED1, TERF1, SETDB1, NIPBL, ATF7, FOXP1, SMC3, STAG1, MLLT1, STAG2, NFATC3, FOXA2, RBBP5, MEIS1, E2F8, ZSCAN16, GTF2B, FOXF1, MEF2C, CDK9, KDM1A, YY1, RELA, TARDBP, ISL1, HIF1A, SKIL, GATA3, MAX, SPIB, ZNF143, HAND2, CEBPG, KDM5B, PKNOX1, ZNF334, NFKB1, PHOX2B, TBX21, AR, NCOR1, BRD4
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:21000000-21025000~~chr21:24875000-24900000,
chr21:24525000-24550000~~chr21:24875000-24900000,
chr21:24575000-24600000~~chr21:24875000-24900000,
chr21:24875000-24900000~~chr21:25025000-25050000,
chr21:24875000-24900000~~chr21:25300000-25325000,
chr21:24875000-24900000~~chr21:25325000-25350000,
chr21:24875000-24900000~~chr21:25350000-25375000,
chr21:24875000-24900000~~chr21:25375000-25400000,
chr21:24894830-24897390~~chr21:25038993-25040888,
chr21:24894830-24897390~~chr21:25215384-25217157,
chr21:24894830-24897390~~chr21:25312872-25315048,
chr21:24894830-24897390~~chr21:25384467-25387269,
chr21:24894830-24897394~~chr21:25039002-25040942,
chr21:24894830-24897394~~chr21:25312901-25315101,
chr21:24894830-24897394~~chr21:25385024-25387052,
chr21:24895174-24897331~~chr21:25312989-25315108,
chr21:24895217-24897409~~chr21:25038938-25040859,
chr21:24895217-24897409~~chr21:25384906-25387309,
chr21:24895246-24897306~~chr21:25385187-25387188,
chr21:24895257-24897346~~chr21:25038912-25040890,
chr21:24895257-24897346~~chr21:25312934-25315135,
chr21:24895257-24897346~~chr21:25384844-25387316,
chr21:24895308-24897338~~chr21:25038912-25040868,
chr21:24895365-24897344~~chr21:25313202-25314755,
chr21:24895401-24897292~~chr21:25385277-25387061,
chr21:24895404-24897444~~chr21:25038898-25041036,
chr21:24895404-24897444~~chr21:25312967-25315286,
chr21:24895404-24897444~~chr21:25384540-25387027,
chr21:24895412-24897320~~chr21:25039014-25040785,
chr21:24895412-24897320~~chr21:25215564-25217094,
chr21:24895412-24897320~~chr21:25312932-25315067,
chr21:24895412-24897374~~chr21:25038926-25041026,
chr21:24895412-24897374~~chr21:25312992-25315465,
chr21:24895412-24897374~~chr21:25384467-25386981,
chr21:24895417-24897339~~chr21:25313184-25314751,
chr21:24895417-24897339~~chr21:25385234-25387033,
chr21:24895431-24897310~~chr21:25038859-25040781,
chr21:24895431-24897366~~chr21:25038878-25040962,
chr21:24895431-24897366~~chr21:25312835-25315056,
chr21:24895431-24897366~~chr21:25384794-25387223,
chr21:24895435-24897297~~chr21:25385320-25387052,
chr21:24895436-24897312~~chr21:25038928-25040817,
chr21:24895436-24897312~~chr21:25385038-25387061,
chr21:24895439-24897330~~chr21:25039058-25040813,
chr21:24895454-24897237~~chr21:25312980-25314897,
chr21:24895454-24897362~~chr21:25313390-25314757,
chr21:24895454-24897362~~chr21:25385185-25387028,
chr21:24895469-24897373~~chr21:25039058-25040876,
chr21:24895469-24897373~~chr21:25312888-25315096,
chr21:24895473-24897247~~chr21:25039094-25040627,
chr21:24895480-24897346~~chr21:25313190-25314774,
chr21:24895510-24897368~~chr21:25038960-25041269,
chr21:24895510-24897368~~chr21:25312968-25315386,
chr21:24895510-24897368~~chr21:25384420-25387034,
chr21:24895560-24897204~~chr21:25038968-25040820,
chr21:24895560-24897204~~chr21:25313326-25315106,
chr21:24895563-24897074~~chr21:25313003-25315176,
chr21:24895582-24897226~~chr21:25313215-25314816,
chr21:24895582-24897226~~chr21:25384605-25386845,
chr21:24895665-24896948~~chr21:25039050-25040629,
chr21:24895738-24897210~~chr21:25038968-25040729,
chr21:24900000-24925000~~chr21:25300000-25325000,
chr21:24900000-24925000~~chr21:25375000-25400000,