- Basic information
- CohesinDB ID: CDBP00415178
- Locus: chr21-25171189-25171972
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Data sourse: GSE103477, GSE111537, GSE126755, GSE55407
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Cell type: OCI-AML-3, Neutrophil, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMARCA2, XBP1, LYL1, ATF3, CBFB, BACH2, JMJD1C, ELF1, TRIM28, TEAD1, ETV1, LMO2, OCA2, CTCF, TCF12, JUN, KLF1, TRIM24, IRF4, TEAD4, KMT2B, POU2F2, POU5F1, RUNX1T1, MLLT3, ERG, HOXC5, MYC, RAD21, GRHL3, GABPA, STAT3, RCOR1, NFE2, ARNTL, VDR, CEBPB, KMT2A, GRHL2, FEZF1, ZHX2, SPI1, INTS13, FLI1, MRTFB, RUNX1, CEBPA, ZFX, SMAD3, SMARCC1, RUNX2, PBX4, ARNT, FOS, CDK8, MED1, MYB, SETDB1, STAT5A, TCF3, MLLT1, SKI, GTF2B, MEF2C, CDK9, KDM1A, RELA, JUNB, HIF1A, OTX2, GATA3, MAX, ZNF143, TP53, MED, NFKB1, PAX3-FOXO1, AR, ZBTB16, EGR1, NOTCH3, BRD4, MAZ, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:17775000-17800000~~chr21:25175000-25200000,
chr21:25025000-25050000~~chr21:25175000-25200000,
chr21:25173538-25175402~~chr21:25273500-25274863,
chr21:25175000-25200000~~chr21:25300000-25325000,
chr21:25175000-25200000~~chr21:25375000-25400000,
chr21:25175000-25200000~~chr21:25475000-25500000,
chr21:25175000-25200000~~chr21:25550000-25575000,
chr21:25175526-25177901~~chr21:25188035-25189709,
chr21:25175526-25177901~~chr21:25297853-25299743,
chr21:25175735-25177434~~chr21:25188189-25189467,
chr21:25176136-25177376~~chr21:25187122-25189516,