- Basic information
- CohesinDB ID: CDBP00415180
- Locus: chr21-25175375-25177516
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Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR000BLY, GSE155324, GSE206145, ENCSR000BMY, ENCSR000EHX, GSE50893
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Cell type: GM12892, GM2630, SNYDER, Lymphoblast, GM19240, GM12878, GM12891, GM2588, GM12890, GM19238, hLCL, GM2255, SK-N-SH, GM19239, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, CBX5, SOX2, BMI1, NFIC, RUNX3, CBFB, PAX5, BACH2, JMJD1C, ELF1, BCLAF1, TEAD1, ZNF26, ETV1, ZNF217, ESR1, OCA2, PITX3, CTCF, TCF12, EP300, DPF2, PAX8, IRF4, TRIM24, RAD51, TEAD4, RBPJ, EED, NANOG, POU2F2, MYCN, POU5F1, TOP2A, MTA2, SRF, NBN, ARID3A, ERG, OGG1, ZNF597, MYC, RAD21, GRHL3, RXRA, BATF3, GABPA, STAT3, IKZF1, RCOR1, CD74, NR3C1, CEBPB, KMT2A, CREB1, EBF3, ZHX2, SPI1, GATA2, GATAD2B, FLI1, SREBF1, SMARCA5, RELB, RUNX1, BCL6, SMC1A, CEBPA, TRIM22, SMARCC1, TWIST1, MEF2A, CREBBP, ZNF384, ZBTB2, ARNT, PBX4, BACH1, ATF2, FOXM1, PBX3, ETV6, FOS, CDK8, MED1, PML, SETDB1, STAT5A, NIPBL, BCL11A, SP1, REST, ATF7, ASH2L, BCOR, TCF3, FOXP1, STAT2, MLLT1, NFATC3, MEF2B, ZNF207, MTA3, EBF1, CREM, NFATC1, CHD2, MEIS1, GTF2B, ZBED1, MEF2C, TCF7, CDK9, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, ISL1, SKIL, GATA3, BATF, MAX, SPIB, HAND2, NR2F1, KDM5B, ZNF687, PKNOX1, PHOX2B, TBX21, BHLHE40, TAF1, RXR, IKZF2, BRD4, JUND, TBX2, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:17775000-17800000~~chr21:25175000-25200000,
chr21:25025000-25050000~~chr21:25175000-25200000,
chr21:25173538-25175402~~chr21:25273500-25274863,
chr21:25175000-25200000~~chr21:25300000-25325000,
chr21:25175000-25200000~~chr21:25375000-25400000,
chr21:25175000-25200000~~chr21:25475000-25500000,
chr21:25175000-25200000~~chr21:25550000-25575000,
chr21:25175526-25177901~~chr21:25188035-25189709,
chr21:25175526-25177901~~chr21:25297853-25299743,
chr21:25175735-25177434~~chr21:25188189-25189467,
chr21:25176136-25177376~~chr21:25187122-25189516,