- Basic information
- CohesinDB ID: CDBP00415184
- Locus: chr21-25188537-25189331
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Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE206145, GSE62063, ENCSR000BMY, GSE103477, GSE50893
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Cell type: GM12892, GM2630, SNYDER, GM2610, GM19240, GM12878, Ramos, GM12891, GM2588, GM12890, GM19238, hLCL, GM2255, GM19239, THP-1, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 89%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, XBP1, TSC22D4, BMI1, NFIC, RUNX3, CBFB, PAX5, BACH2, BCLAF1, ZNF217, ESR1, OCA2, CTCF, TCF12, EP300, DPF2, IRF4, RBPJ, EED, POU2F2, MTA2, DUX4, SRF, ARID3A, ZNF597, MYC, ZKSCAN2, RAD21, RXRA, BATF3, GABPA, STAT3, IKZF1, NR3C1, CEBPB, CREB1, EPAS1, SPI1, GATAD2B, RELB, SMC1A, BCL6, POU4F2, MEF2A, CREBBP, ZBTB2, GATA4, ARNT, SOX11, ATF2, FOXM1, ETV6, CDK8, MED1, PML, SETDB1, STAT5A, BCL11A, SP1, NIPBL, HNF4A, REST, ATF7, ASH2L, BCOR, TCF3, NFATC3, MEF2B, MTA3, EBF1, CREM, NFATC1, ZBED1, GTF2B, MEF2C, TCF7, ZBTB33, BCL3, YY1, RELA, JUNB, SKIL, BATF, SPIB, NR2F1, TBX21, BHLHE40, IKZF2, BRD4, JUND, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:17775000-17800000~~chr21:25175000-25200000,
chr21:25025000-25050000~~chr21:25175000-25200000,
chr21:25175000-25200000~~chr21:25300000-25325000,
chr21:25175000-25200000~~chr21:25375000-25400000,
chr21:25175000-25200000~~chr21:25475000-25500000,
chr21:25175000-25200000~~chr21:25550000-25575000,
chr21:25175526-25177901~~chr21:25188035-25189709,
chr21:25175735-25177434~~chr21:25188189-25189467,
chr21:25176136-25177376~~chr21:25187122-25189516,
chr21:25185361-25187101~~chr21:25215615-25217170,
chr21:25188035-25189709~~chr21:25297853-25299743,