- Basic information
- CohesinDB ID: CDBP00415187
- Locus: chr21-25197050-25197736
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Data sourse: GSE103477, GSE111537, GSE55407
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Cell type: OCI-AML-3, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, POU2F2, TOP2A, MEIS1, ZFX, GTF2B, SMAD3, FOXA1, MLLT3, MEF2C, CDK9, HOXB13, HOXC5, RELA, CREBBP, ZNF384, LYL1, OGG1, MYC, RAD21, ARNT, PBX4, PRDM9, BATF, MAX, PAX5, SPIB, CDK8, MED1, VDR, NR3C1, JMJD1C, KMT2A, ETV1, SCRT2, LMO2, MLL, MED, STAT5A, JUN, TCF12, CTCF, SPI1, AR, TRIM24, HOXA9, BRD4, JUND, SCRT1, TCF3, MLLT1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops