- Basic information
- CohesinDB ID: CDBP00415189
- Locus: chr21-25215920-25216587
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Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR000BLY, GSE155324, GSE206145, ENCSR000BMY, ENCSR000EHX, GSE50893, ENCSR917QNE
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Cell type: GM12892, SNYDER, Lymphoblast, GM12878, GM12891, SK-N-SH, Liver, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CBX5, MEF2B, BCL6, FOXA2, POU2F2, EBF1, TOP2A, CREM, SMC1A, MTA2, DUX4, FOXA1, SRF, MEF2C, CDK9, ARID3A, ERG, MEF2A, CREBBP, ZBTB2, JUNB, NFIC, MYC, RUNX3, RAD21, GRHL3, ATF2, BATF, STAT3, MAX, FOXM1, PAX5, CDK8, MED1, CEBPB, TERF1, BCLAF1, KMT2A, CREB1, STAT5A, CTCF, NIPBL, SPI1, BCL11A, TBX21, AR, IRF4, ATF7, ASH2L, BRD4, BCOR, FOXP1, NCOR2, MLLT1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops