- Basic information
- CohesinDB ID: CDBP00415196
- Locus: chr21-25283113-25284711
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Data sourse: ENCSR000BLD, ShirahigeLab-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000DZP, ENCSR000EAC, GSE139435, GSE165895, GSE115250, GSE138405, GSE67783, GSE86191, GSE76893, GSE152721, GSE135093, ShirahigeLab-NatGen2015, GSE120943, GSE112028, GSE138105, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE93080, GSE94872, ENCSR000EEG, ENCSR000EHW, GSE85526, ENCSR000ECE, ShirahigeLab, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR000HPG, GSE111913, GSE155324, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS
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Cell type: MDM, RH4, GM10847, GM2610, SLK, GM19240, HSPC, CVI-hiPSC, Liver, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, THP-1, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, HUVEC, GM19238, TC-71, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 32% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.389
- Subunit: SA1,Rad21,SMC3,SMC1,SA2,SMC3ac
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, SMC1A, POU5F1, CDK7, STAG2, GTF2B, DUX4, SRF, ZNF654, HOXB13, YY1, ZBTB2, MYC, CTCFL, CHD7, RAD21, RUNX3, HIF1A, MAX, ZNF143, NR3C1, ESR1, CTCF, ZHX2, BCL11A, AR, EGLN2, SIX2, BRD4, BCOR, FOXP1, SMC1, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops