- Basic information
- CohesinDB ID: CDBP00415209
- Locus: chr21-25360555-25361481
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Data sourse: ENCSR000BLD, GSE25021, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, GSE50893, ENCSR000BMY, GSE111537, GSE145327, GSE108869, GSE97394, GSE55407
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Cell type: GM2610, GM19240, H9-hESC, GM2630, Fibroblast, GM12890, HeLa-S3, GM2255, GM18486, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, THP-1, GM19099, HUES64, MCF-7, GM12892, GM19238, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ZBTB2, SMC1A, GATA2, IRF4, RAD21, TCF4, HIF1A, OTX2, FOXA1, SRF, SETDB1, SMC3, CTCF, HOXC5
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops