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Basic information

CohesinDB ID: CDBP00415213

Locus: chr21-25373228-25373956

Data sourse: GSE105028, GSE206145-NatGen2015, GSE120943, GSE206145

Cell type: RPE, Fibroblast, Monocytes, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 63%, "7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NANOG, PGR, CHD8, FOXA2, RBBP5, SOX2, NME2, FOXA1, ERG3, ERG2, HNRNPK, YY1, KDM1A, MYC, CDK6, GATA4, CHD7, GRHL3, DAXX, PBX4, MAX, NR3C1, SAP30, ESR1, EGR2, TCF12, SP1, TAF1, PCBP1, GATA2, ASH2L, BRD4, TEAD4

Target gene symbol (double-evidenced CRMs): APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000142192,

eachgene

Deatailed information for cohesin site CDBP00415213