- Basic information
- CohesinDB ID: CDBP00415241
- Locus: chr21-25495684-25498394
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Data sourse: GSE93080, ENCSR000EAC, GSE67783, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR000BMY, GSE50893
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Cell type: GM2630, Fibroblast, GM10847, GM2610, GM12878, GM2588, GM19238, GM19239, HSPC, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 82%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, SMC1A, EBF1, TOP2A, CREM, ZFX, CRY1, HNF1A, MTA2, ZSCAN5A, FOXA1, NBN, CDK9, ERG, RELA, HDGF, ZNF384, TARDBP, JUNB, ATF3, MYC, NFIC, RUNX2, RUNX3, GRHL3, SKIL, ARNT, HIF1A, NKX2-1, ATF2, GATA3, BATF, SMC3, SMARCE1, PAX5, FOS, IKZF1, MED1, NR3C1, CEBPB, BCLAF1, TRIM28, NR2F1, STAG1, OCA2, SETDB1, EBF3, CTCF, ZHX2, TCF12, SPI1, NIPBL, BCL11A, AR, DPF2, ARID1A, IRF4, FOSL2, FLI1, ATF7, HOXA9, BRD4, IKZF2, JUND, TCF3, NOTCH3, RELB, ZIM3, ZNF175, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 21
- Related genes and loops