- Basic information
- CohesinDB ID: CDBP00415245
- Locus: chr21-25509838-25510553
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Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR000BMY, GSE50893
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Cell type: GM12892, hLCL, GM12878, GM12891
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 90%,
"7_Enh": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, XBP1, FOXA1, TSC22D4, NFIC, CHD7, RUNX3, CBFB, PAX5, CDX2, MAF, TEAD1, BCLAF1, TRIM28, SMAD5, USF2, JUN, TCF12, CTCF, SND1, GATA6, IRF4, RAD51, E2F1, PDX1, RBPJ, EED, POU2F2, TOP2A, DUX4, SRF, NBN, ARID3A, ERG2, TBP, HOXC5, ERG, ASCL1, ZNF597, NFKB2, MYC, RAD21, NKX2-1, FOXK2, STAT3, NKX3-1, IKZF1, RCOR1, NR3C1, CEBPB, STAT5B, CREB1, ZHX2, SPI1, EHF, GATA2, DRAP1, RELB, RUNX1, SMC1A, BCL6, CEBPA, NKX2-2, SIN3A, SMAD3, TRIM22, MEF2A, ZBTB2, CREBBP, ZNF384, GATA4, PBX4, DAXX, ATF2, PRDM9, PBX3, FOXM1, ETV6, FOS, CDK8, MED1, PML, SMAD1, NR1H2, SETDB1, STAT5A, ZNF22, MAFK, BCL11A, SP1, NIPBL, REST, ATF7, ASH2L, STAT2, MLLT1, NFATC3, MEF2B, FOXA2, MTA3, EBF1, CREM, NFATC1, E2F8, ZBED1, GTF2B, MEF2C, TCF7, HOXB13, BCL3, YY1, RELA, TARDBP, JUNB, HIF1A, SKIL, GATA3, BATF, MAX, GATA1, PKNOX1, ZNF334, NFKB1, MYOD1, TBX21, BHLHE40, AR, TAF1, ZBTB40, EGR1, IKZF2, JUND, BRD4, CLOCK, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops