- Basic information
- CohesinDB ID: CDBP00415248
- Locus: chr21-25512342-25513269
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Data sourse: GSE50893, ENCSR000BMY, GSE120943, GSE98367
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Cell type: GM2610, GM12878, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 93%,
"7_Enh": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, CDK9-HEXIM1, MEF2B, POU2F2, SMC1A, POU5F1, EBF1, ZFX, ZBED1, WT1, STAT1, FOXA1, NBN, CDK9, TRIM22, BCL3, YY1, RELA, HDGF, TSC22D4, ZNF384, TARDBP, MYC, RUNX3, RAD21, MCM3, CHD7, CBFB, ATF2, STAT3, PAX5, NKX3-1, IKZF1, MED1, VDR, JMJD1C, BCLAF1, TRIM28, SMAD1, ZNF687, PKNOX1, USF2, SETDB1, CTCF, SND1, TCF12, NIPBL, SPI1, SP1, AR, GATA2, IRF4, RAD51, BRD4, SCRT1, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops