- Basic information
- CohesinDB ID: CDBP00415339
- Locus: chr21-25907805-25908312
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Data sourse: ENCSR230ZWH, ENCSR000BLY, ENCSR000EHW, ENCSR000EHX, ENCSR917QNE
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Cell type: Liver, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 59%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, PPARG, FOXA2, NKX2-2, EBF1, TOP2A, SOX2, LDB1, DUX4, FOXA1, CDK9, HOXB13, ERG, YY1, RELA, KDM1A, ZNF384, HOXC5, BCL11A, MYC, RAD21, GRHL3, HIF1A, RXRA, OTX2, GATA3, GABPA, TAL1, PBX3, MAFB, NKX3-1, ZNF143, AGO2, RCOR1, CDX2, TLE3, CEBPB, TRIM28, MYB, CREB1, PIAS1, TCF7L2, LMO2, TP53, ESR1, PITX3, EBF3, JUN, RBM22, TCF12, SP1, SPI1, BAF155, EP300, AR, HNF4A, CTCF, GATA6, NR4A1, GATA2, PAX8, POU2F3, ASH2L, MXI1, BRD4, TCF3, FOXP1, TEAD4, PDX1
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 32
- Number of somatic mutations (non-coding): 0
- Related genes and loops