- Basic information
- CohesinDB ID: CDBP00415347
- Locus: chr21-25930042-25930439
-
Data sourse: ENCSR000BLD, GSE67783, ENCSR000BKV, GSE86191, GSE105028, ENCSR000ECE, GSE83726, GSE116344, GSE165895
-
Cell type: H1-hESC, HCT-116, RH4, H9-hESC, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 41%,
"7_Enh": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PAX7, PGR, CHD8, PPARG, POU2F2, POU5F1, TOP2A, SOX2, ZFX, POU4F2, XBP1, ZSCAN16, DUX4, ZSCAN5A, PAF1, GTF2B, TEAD4, ERG, YY1, RELA, CREBBP, JUNB, RUNX2, MYC, RAD21, CHD7, GRHL3, RXRA, ATF2, MAX, TP63, FOS, VDR, KLF4, TRIM28, KMT2A, MYB, SCRT2, TP53, ZIM3, GRHL2, ZNF334, USF2, SETDB1, MYOD1, JUN, RBM22, CTCF, SPI1, AR, POU2F3, FLI1, BRD4, SCRT1, TCF3, E2F1, MAZ, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 2
- Related genes and loops