- Basic information
- CohesinDB ID: CDBP00415348
- Locus: chr21-25931631-25932182
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Data sourse: GSE126634, GSE152721
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Cell type: HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 52%,
"15_Quies": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PAX7, PGR, CHD8, PPARG, POU2F2, POU5F1, TOP2A, SOX2, ZFX, POU4F2, XBP1, ZSCAN16, DUX4, ZSCAN5A, PAF1, GTF2B, TEAD4, ERG, YY1, RELA, CREBBP, JUNB, RUNX2, MYC, RAD21, CHD7, GRHL3, RXRA, ATF2, MAX, TP63, FOS, VDR, KLF4, TRIM28, KMT2A, MYB, SCRT2, TP53, ZIM3, GRHL2, ZNF334, USF2, SETDB1, MYOD1, JUN, RBM22, CTCF, SPI1, AR, POU2F3, FLI1, BRD4, SCRT1, TCF3, E2F1, MAZ, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 2
- Related genes and loops