- Basic information
- CohesinDB ID: CDBP00415350
- Locus: chr21-25936970-25937197
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Data sourse: GSE206145-NatGen2015, ENCSR000BLY
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Cell type: Fibroblast, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, POU5F1, TOP2A, PAF1, TEAD4, ZFX, SMAD3, ZBTB48, FOXA1, ZNF770, SRF, DDX5, ZNF823, HOXB13, SMARCC1, ERG, HOXC5, RELA, OGG1, JUNB, NEUROD1, RUNX2, SMAD2, ZFP64, MYC, ETS1, CHD7, LHX2, ISL1, NFIC, ZBTB44, RXRA, OTX2, GATA3, GABPA, PBX3, PAX5, MAX, FOS, TP63, IKZF1, HAND2, ARNTL, KLF4, ESRRA, NR2F2, KLF6, SNAI2, GRHL2, EBF3, JUN, CTCF, ELF3, RBM22, SPI1, TCF12, BAF155, EP300, IRF1, AR, GATA2, POU2F3, FLI1, NCOR1, ZNF548, BRD4, FOXP1, SMC1, ZIM3, RBPJ, FOSL2
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 2
- Related genes and loops