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Basic information

CohesinDB ID: CDBP00415353

Locus: chr21-25948503-25949092

Data sourse: GSE126634, GSE206145-GSE177045, GSE152721, ENCSR000BLY

Cell type: MCF-7, HAP1, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 72%, "15_Quies": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PPARG, FOXA2, POU5F1, CEBPA, SOX2, PAF1, XBP1, FOXA1, ZBTB33, HOXB13, HNF4G, YY1, RELA, ATF3, MYC, SMARCA4, RAD21, RXRA, OTX2, GATA3, NKX2-1, PROX1, MAX, SOX10, AGO2, ZNF736, CDX2, CEBPB, NR2F2, TFAP2C, SNAI2, ESR1, RBM22, SP1, HNF4A, AR, GATA6, GATA2, EGR1, BRD4, JUND, SMC3, NCOR2, AHR

Target gene symbol (double-evidenced CRMs): APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 32

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142192,

eachgene

Deatailed information for cohesin site CDBP00415353