- Basic information
- CohesinDB ID: CDBP00415416
- Locus: chr21-26133563-26133797
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Data sourse: GSE206145-NatGen2015, GSE111913, GSE86191
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Cell type: RT-112, Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 66%,
"15_Quies": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, POU5F1, LDB1, ZFX, XBP1, WT1, DUX4, ZNF770, KDM1A, RELA, NEUROD1, GATA4, ISL1, GRHL3, HIF1A, OTX2, HMGB2, GATA3, TAL1, STAT3, GATA1, ZNF143, MITF, HAND2, SAP30, PHOX2B, RBM22, USF1, BCL11A, NR4A1, PAX3-FOXO1, GATA6, PAX8, GATA2, POU2F3, FLI1, BRD4, PHIP, FOXP1
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops