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Basic information

CohesinDB ID: CDBP00415421

Locus: chr21-26146681-26147011

Data sourse: GSE206145-GSE177045

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 72%, "15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, SOX2, XBP1, FOXA1, TFAP4, ATF3, CHD7, MZF1, MITF, ZNF467, JMJD1C, TEAD1, ETV1, KLF6, SAP30, ESR1, HNF1B, OCA2, PITX3, LMO2, JUN, TCF12, BAF155, EP300, LMO1, GATA6, DPF2, E2F1, TEAD4, FOXA3, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, TOP2A, CDK7, RUNX1T1, DUX4, STAT1, ERG, ASCL1, ETS1, MYC, ONECUT1, EOMES, SMARCA4, RAD21, GRHL3, PROX1, NKX2-1, RXRA, GABPA, STAT3, RCOR1, NR2F6, VDR, ARNTL, NR3C1, ESRRA, CEBPB, KMT2A, BMPR1A, GRHL2, TRPS1, ZHX2, SPI1, MIXL1, EHF, IRF1, KLF17, HDAC2, GATA2, FLI1, MRTFB, RUNX1, SMC1A, CEBPA, SIN3A, ZFX, ZNF534, SMAD3, ERG3, SMARCC1, PRDM10, CREBBP, NOTCH1, RUNX2, CDK6, GATA4, ZNF184, ARNT, PBX4, SOX11, HMGB2, ATF2, FOXM1, CHD1, CDK8, FOS, MED1, ZEB1, TEAD3, MYB, SCRT2, TBX5, RBM22, BCL11A, NR4A1, REST, ARID1A, ZNF479, ASH2L, HNRNPLL, PHIP, TCF3, FOXP1, PRDM6, ELL2, NCOR2, FOXA2, RBBP5, EBF1, PAF1, CDK9, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, ISL1, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, HAND2, KLF4, NCOA3, NR2F2, TCF7L2, KDM5B, TP53, NFKB1, MYOD1, PHOX2B, ELF3, BRD2, AR, PAX3-FOXO1, YAP1, RXR, EGLN2, NOTCH3, SCRT1, BRD4, JUND, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142192,

eachgene

Deatailed information for cohesin site CDBP00415421