- Basic information
- CohesinDB ID: CDBP00415591
- Locus: chr21-26909720-26911181
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE138405, GSE152721, GSE135093, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, GSE116344, GSE106870, GSE138105, GSE145327, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE105004, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS, GSE64758
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Cell type: RH4, SLK, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, IMR-90, H1-hESC, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, Hela-Kyoto, HEK293T, Neurons-H1, HeLa, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 15% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.733
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 71%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, NANOG, POU5F1, RBBP5, NKX2-2, SOX2, TEAD4, POU4F2, XBP1, GTF2B, ZNF317, SMAD3, FOXA1, SRF, HOXB13, SMARCC1, ERG, KDM1A, YY1, SMAD2, BRG1, CHD7, RAD21, HIF1A, TFDP1, ATF2, GATA3, MAX, MED1, ARNTL, NR3C1, TEAD1, CTCF, T, MAFK, SP1, EP300, NIPBL, BCL11A, AR, HDAC2, YAP1, ASH2L, CTBP2, BRD4, BCOR, SMC3
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops