- Basic information
- CohesinDB ID: CDBP00415626
- Locus: chr21-27058546-27060652
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Data sourse: GSE138405, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS
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Cell type: RPE, Hela-Kyoto, Fibroblast, HeLa-S3, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 84%,
"7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, NKX2-2, ZSCAN16, DUX4, MAFF, FOXA1, HOXB13, RELA, JUNB, RUNX2, GATA4, RAD21, PBX4, GABPA, STAT3, NKX3-1, FOS, MED1, VDR, NR3C1, CEBPB, NR2F2, TCF7L2, NFKB1, ELF3, NUP98-HOXA9, MAFK, EP300, CTCF, JUN, HES1, AR, GATA6, GATA2, RFX5, BRD4, JUND, PDX1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 24
- Related genes and loops