- Basic information
- CohesinDB ID: CDBP00415681
- Locus: chr21-27276725-27277972
-
Data sourse: ENCSR230ZWH, GSE98367, GSE138405, GSE206145, GSE206145-NatGen2015, GSE120943, GSE126990, ENCSR917QNE
-
Cell type: RPE, Hela-Kyoto, Fibroblast, Monocytes, Liver, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 77%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, CEBPA, NME2, FOXF1, FOXA1, SMARCC1, HNRNPK, YY1, RELA, RUNX2, MYC, GATA4, RAD21, GRHL3, HIF1A, DAXX, RXRA, GATA3, MAX, FOS, MED1, NR3C1, CEBPB, NR2F2, PIAS1, ESR1, MAFK, SP1, USF1, SPI1, BHLHE40, HNF4A, GATA6, ZBTB16, GATA2, HSF1, NOTCH3, BRD4, SMC3, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops