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Basic information

CohesinDB ID: CDBP00415697

Locus: chr21-27345866-27347069

Data sourse: GSE206145, GSE206145-NatGen2015, GSE165895

Cell type: RPE, Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, POU5F1, SOX2, SMAD3, DUX4, SMARCC1, HOXC5, JUNB, RUNX2, NRF1, HIF1A, GATA3, ZNF383, MAX, FOS, NFE2, MED1, NR3C1, CEBPB, TEAD1, NFE2L2, BRD2, JUN, TCF12, MAFK, BRD4, JUND, E2F1, TEAD4, FOSL2

Target gene symbol (double-evidenced CRMs): LTN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene: ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415697