- Basic information
- CohesinDB ID: CDBP00415738
- Locus: chr21-27504825-27506541
-
Data sourse: GSE105004, GSE138405, ENCSR000EHW, GSE206145-NatGen2015, GSE206145, ENCSR000EHX, GSE116344, GSE126990, GSE165895
-
Cell type: RPE, Hela-Kyoto, Fibroblast, RH4, HeLa, SK-N-SH, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 83%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: OTX2, NEUROG2
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 15
- Related genes and loops
- Related gene:
ENSG00000142192,
- Related loop:
chr21:10325000-10350000~~chr21:27500000-27525000,
chr21:14875000-14900000~~chr21:27500000-27525000,
chr21:17500000-17525000~~chr21:27500000-27525000,
chr21:17675000-17700000~~chr21:27500000-27525000,
chr21:22725000-22750000~~chr21:27500000-27525000,
chr21:24450000-24475000~~chr21:27500000-27525000,
chr21:24675000-24700000~~chr21:27500000-27525000,
chr21:26150000-26175000~~chr21:27500000-27525000,
chr21:26175000-26200000~~chr21:27500000-27525000,
chr21:26850000-26875000~~chr21:27475000-27500000,
chr21:27100000-27125000~~chr21:27475000-27500000,
chr21:27300000-27325000~~chr21:27475000-27500000,
chr21:27350000-27375000~~chr21:27500000-27525000,
chr21:27475000-27500000~~chr21:28325000-28350000,
chr21:27475000-27500000~~chr21:28725000-28750000,
chr21:27500000-27525000~~chr21:29725000-29750000,
chr21:27500000-27525000~~chr21:29750000-29775000,
chr21:27500000-27525000~~chr21:30200000-30225000,
chr21:27500000-27525000~~chr21:30575000-30600000,
chr21:27500000-27525000~~chr21:30700000-30725000,
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:27500000-27525000~~chr21:31500000-31525000,
chr21:27500000-27525000~~chr21:31650000-31675000,
chr21:27500000-27525000~~chr21:32000000-32025000,
chr21:27500000-27525000~~chr21:32100000-32125000,
chr21:27500000-27525000~~chr21:32350000-32375000,
chr21:27500000-27525000~~chr21:33250000-33275000,
chr21:27500000-27525000~~chr21:33475000-33500000,
chr21:27500000-27525000~~chr21:34350000-34375000,
chr21:27500000-27525000~~chr21:34525000-34550000,
chr21:27500000-27525000~~chr21:36125000-36150000,
chr21:27500000-27525000~~chr21:36275000-36300000,
chr21:27500000-27525000~~chr21:36625000-36650000,
chr21:27500000-27525000~~chr21:38850000-38875000,
chr21:27500000-27525000~~chr21:39275000-39300000,
chr21:27500000-27525000~~chr21:42750000-42775000,
chr21:27500000-27525000~~chr21:42925000-42950000,
chr21:27500000-27525000~~chr21:43000000-43025000,
chr21:27500000-27525000~~chr21:44275000-44300000,
chr21:27500000-27525000~~chr21:44625000-44650000,
chr21:27500000-27525000~~chr21:44650000-44675000,
chr21:27500000-27525000~~chr21:44775000-44800000,
chr21:27500000-27525000~~chr21:44825000-44850000,
chr21:27500000-27525000~~chr21:45025000-45050000,
chr21:27500000-27525000~~chr21:45225000-45250000,
chr21:27500000-27525000~~chr21:45550000-45575000,
chr21:27500000-27525000~~chr21:46075000-46100000,