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Basic information

CohesinDB ID: CDBP00415787

Locus: chr21-27772650-27773277

Data sourse: GSE206145, GSE206145-NatGen2015

Cell type: RPE, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 24% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 89%, "7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, PPARG, CEBPA, NME2, FOXA1, MEF2C, HOXB13, SMARCC1, ERG, MEF2A, RELA, JUNB, NEUROD1, NFIC, GATA4, CHD7, RAD21, GRHL3, RXRA, OTX2, GATA3, GABPA, TAL1, PBX3, FOS, CDK8, MED1, NR3C1, JMJD1C, CEBPB, NR2F2, LMO2, ESR1, MLL, PHOX2B, JUN, CTCF, TCF12, SPI1, SP1, EP300, EGLN2, FLI1, BRD4, JUND, SMC1, KMT2B, MLLT1, FOSL2

Target gene symbol (double-evidenced CRMs): LTN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene: ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415787