- Basic information
- CohesinDB ID: CDBP00415795
- Locus: chr21-27805451-27806647
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Data sourse: GSE98367, GSE120943, GSE165895
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Cell type: Monocytes, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 77%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, ZNF283, PGR, CHD8, SMC1A, FOXA2, NKX2-2, NME2, XBP1, GTF2B, FOXA1, FOXF1, ZNF205, DDX5, HOXB13, ZNF596, SMARCC1, ERG, HNF4G, RELA, TFAP4, ZNF384, HOXC5, RUNX2, MYC, BRG1, GATA4, RAD21, MCM3, GRHL3, HIF1A, PBX4, ARNT, RXRA, GATA3, PRDM9, GABPA, PBX3, MAX, NKX3-1, FOS, RCOR1, HDAC3, ARNTL, TLE3, NR3C1, CEBPB, TEAD1, NR2F2, CREB1, PIAS1, KDM5B, ESR1, OCA2, PHOX2B, SP1, BAF155, SPI1, AR, PAX3-FOXO1, HDAC2, GATA2, ARID1A, IRF4, HSF1, ASH2L, BRD4, CTBP2, FOXP1, TEAD4, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 17
- Related genes and loops
- Related gene:
- Related loop:
chr21:26848688-26851432~~chr21:27802305-27803923,
chr21:26848717-26851115~~chr21:27802133-27803841,
chr21:26848717-26851211~~chr21:27802381-27803695,
chr21:26848765-26851527~~chr21:27802176-27803976,
chr21:26848770-26851390~~chr21:27802290-27803924,
chr21:26848947-26851347~~chr21:27802087-27803810,
chr21:26848956-26852143~~chr21:27802108-27803785,
chr21:26880663-26882691~~chr21:27802305-27803923,
chr21:26881095-26882278~~chr21:27802335-27803696,
chr21:27800000-27825000~~chr21:27950000-27975000,
chr21:27800000-27825000~~chr21:28725000-28750000,
chr21:27802121-27804049~~chr21:28335748-28338250,