- Basic information
- CohesinDB ID: CDBP00415830
- Locus: chr21-27954678-27955331
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Data sourse: GSE165895, GSE111537, GSE206145, GSE138105
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Cell type: RPE, SLK, OCI-AML-3, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 90%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SMARCA2, XBP1, HNF1A, FOXA1, HNRNPK, CHD7, ZNF322, ZSCAN4, JMJD1C, ELF1, TRIM28, ESR1, HNF1B, CTCF, BAF155, PAX8, KMT2B, RBPJ, TFAP2C, POU2F2, DUX4, DDX5, ERG, MYC, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, STAT3, ARNTL, VDR, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, SPI1, INTS13, ZNF182, GATA2, FLI1, ZNF777, RUNX1, CTNNB1, BCL6, CEBPA, SMARCC1, ZNF384, CDK6, GATA4, CDK8, MYB, PIAS1, SETDB1, EVI1, STAT5A, BCL11A, NR4A1, REST, ASH2L, SRSF9, FOXP1, NCOR2, MLLT1, SKI, FOXA2, SS18, FOXF1, MEF2C, ZBTB33, CDK9, HOXB13, KDM1A, RELA, BRG1, TCF4, HIF1A, GATA3, TAL1, MAF1, KLF4, NR2F2, TCF7L2, MED, ZNF334, AR, NCOR1, NOTCH3, BRD4, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops