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Basic information

CohesinDB ID: CDBP00415860

Locus: chr21-28078861-28079357

Data sourse: GSE98367, ENCSR000BLY, ENCSR404BPV, GSE120943, ENCSR000EHX

Cell type: Neurons-H1, Monocytes, Macrophage, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SMC3,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 98%, "9_Het": 1%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SOX2, FOXA1, PBX2, ATF3, ATF4, ZSCAN4, HDAC3, CDX2, ESR1, OCA2, CTCF, TCF12, BAF155, EP300, GATA6, TEAD4, ZNF175, TFAP2C, NANOG, POU5F1, MYCN, DUX4, ZNF205, DDX5, ERG, MYC, RAD21, GRHL3, GABPA, NKX3-1, RCOR1, NR3C1, CEBPB, CREB1, EBF3, HDAC2, GATA2, FLI1, ZIM3, RUNX1, CTNNB1, CEBPA, SMARCC1, ZNF384, CDK6, GATA4, GR, ARNT, ATF2, PRDM9, PBX3, PIAS1, NCOA1, POU2F3, ASH2L, FOXP1, PAX7, FOXA2, CHD2, FOXF1, HOXB13, KDM1A, ZNF19, RELA, YY1, BRG1, ISL1, TCF4, OTX2, GATA3, TAL1, HAND2, TLE3, CEBPG, PKNOX1, PHOX2B, AR, TAF1, EGLN2, MAML3, NCOR1, BRD4, TBX2, AHR

Target gene symbol (double-evidenced CRMs): LTN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415860