- Basic information
- CohesinDB ID: CDBP00415868
- Locus: chr21-28097109-28097588
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE25021, GSE131606, ENCSR000EDW, ENCSR917QNE, ENCSR000BTU, GSE206145-NatGen2015, GSE116344, GSE98367, GSE206145, ENCSR000ECE, ENCSR000EHX, ENCSR000BTQ, ENCSR167MTG, ENCSR054FKH, ENCSR000EDE, GSE68388
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Cell type: MCF-7, H1-hESC, Macrophage, Fibroblast, MDM, RH4, Hep-G2, RPE, Ishikawa, DKO, HeLa-S3, SK-N-SH, Liver, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 94%,
"5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, AR, TRIM28, TWIST1
- Target gene symbol (double-evidenced CRMs): LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000198862,
- Related loop:
chr21:28075000-28100000~~chr21:28225000-28250000,
chr21:28075000-28100000~~chr21:28300000-28325000,
chr21:28075000-28100000~~chr21:28325000-28350000,
chr21:28075000-28100000~~chr21:28500000-28525000,
chr21:28075000-28100000~~chr21:28700000-28725000,
chr21:28075000-28100000~~chr21:28725000-28750000,
chr21:28075000-28100000~~chr21:28925000-28950000,
chr21:28096589-28098118~~chr21:28335562-28338194,
chr21:28096733-28098046~~chr21:28741591-28743796,
chr21:28100000-28125000~~chr21:28225000-28250000,
chr21:28100000-28125000~~chr21:28300000-28325000,
chr21:28100000-28125000~~chr21:28325000-28350000,
chr21:28100000-28125000~~chr21:28425000-28450000,
chr21:28100000-28125000~~chr21:28500000-28525000,
chr21:28100000-28125000~~chr21:28725000-28750000,