- Basic information
- CohesinDB ID: CDBP00415871
- Locus: chr21-28099075-28100393
-
Data sourse: ENCSR230ZWH, GSE62063, GSE83726, GSE116344, ENCSR917QNE
-
Cell type: Liver, RH4, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 78%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PGR, SMC1A, MYCN, LDB1, ZSCAN16, GTF2B, XBP1, FOXA1, HOXB13, ERG, KDM1A, RELA, CREBBP, ZNF384, ZNF19, NEUROD1, RUNX2, CDK6, SMARCA4, RAD21, FOXP2, GRHL3, HIF1A, RXRA, OTX2, GABPA, MAX, MED1, ARNTL, NR2F2, NEUROG2, MYOD1, ZNF22, CTCF, PHOX2B, BCL11A, SP1, SPI1, HNF4A, AR, GATA2, POU2F3, NCOR1, NOTCH3, BRD4, SCRT1, TEAD4, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): LTN1
- Function elements
- Human SNPs: Acute_anterior_uveitis_in_ankylosing_spondylitis
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000198862,
- Related loop:
chr21:28075000-28100000~~chr21:28225000-28250000,
chr21:28075000-28100000~~chr21:28300000-28325000,
chr21:28075000-28100000~~chr21:28325000-28350000,
chr21:28075000-28100000~~chr21:28500000-28525000,
chr21:28075000-28100000~~chr21:28700000-28725000,
chr21:28075000-28100000~~chr21:28725000-28750000,
chr21:28075000-28100000~~chr21:28925000-28950000,
chr21:28096589-28098118~~chr21:28335562-28338194,
chr21:28096733-28098046~~chr21:28741591-28743796,
chr21:28100000-28125000~~chr21:28225000-28250000,
chr21:28100000-28125000~~chr21:28300000-28325000,
chr21:28100000-28125000~~chr21:28325000-28350000,
chr21:28100000-28125000~~chr21:28425000-28450000,
chr21:28100000-28125000~~chr21:28500000-28525000,
chr21:28100000-28125000~~chr21:28725000-28750000,