- Basic information
- CohesinDB ID: CDBP00415881
- Locus: chr21-28135485-28136292
-
Data sourse: GSE103477, GSE62063, GSE98367
-
Cell type: MDM, THP-1, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 94%,
"7_Enh": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOXO1, ZNF394, POU2F2, SMC1A, PGR, CEBPA, BCL6, EZH2phosphoT487, NANOG, FOXA2, ZFX, NME2, MYCN, XBP1, DUX4, STAT1, FOXA1, BAHD1, HOXB13, TWIST1, ERG, KDM1A, RELA, TFAP4, NFIC, MYC, GATA4, RAD21, PRDM1, TOP1, GRHL3, ISL1, TCF4, LHX2, GATA3, PBX4, GABPA, STAT3, MAX, PAX5, NKX3-1, ZNF143, FOS, PBX3, CDK8, HAND2, VDR, TLE3, NR3C1, CEBPB, TRIM28, KMT2A, CREB1, PIAS1, ETV1, SETDB1, EBF3, MYOD1, PHOX2B, JUN, NUP98-HOXA9, TCF12, SPI1, BAF155, EP300, AR, GATA6, INTS13, GATA2, ARID1A, MAML3, POU2F3, BRD4, JUND, FOXP1, MRTFB, TEAD4, TBX2, MYF5
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops