- Basic information
- CohesinDB ID: CDBP00415882
- Locus: chr21-28136541-28137490
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Data sourse: GSE206145-NatGen2015, GSE62063, GSE165895
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Cell type: Fibroblast, Ramos, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 94%,
"7_Enh": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, ZNF394, POU2F2, SMC1A, PGR, CEBPA, BCL6, EZH2phosphoT487, NANOG, FOXA2, ZFX, NME2, MYCN, XBP1, DUX4, STAT1, FOXA1, BAHD1, HOXB13, TWIST1, ERG, KDM1A, RELA, TFAP4, NFIC, MYC, GATA4, RAD21, PRDM1, TOP1, GRHL3, ISL1, TCF4, LHX2, GATA3, PBX4, GABPA, STAT3, MAX, PAX5, NKX3-1, ZNF143, FOS, PBX3, CDK8, HAND2, VDR, TLE3, NR3C1, CEBPB, TRIM28, KMT2A, CREB1, PIAS1, ETV1, SETDB1, EBF3, MYOD1, PHOX2B, JUN, NUP98-HOXA9, TCF12, SPI1, BAF155, EP300, AR, GATA6, INTS13, GATA2, ARID1A, MAML3, POU2F3, BRD4, JUND, FOXP1, MRTFB, TEAD4, TBX2, MYF5
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 14
- Related genes and loops