- Basic information
- CohesinDB ID: CDBP00415884
- Locus: chr21-28142183-28143484
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Data sourse: ENCSR000EFJ, GSE98367, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE55407, GSE120943, GSE68388, ENCSR000ECS, GSE165895
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Cell type: RPE, Macrophage, Fibroblast, Monocytes, HeLa-S3, IMR-90, SK-N-SH, THP-1, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TOP2A, RUNX2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops