- Basic information
- CohesinDB ID: CDBP00415895
- Locus: chr21-28192770-28193616
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE131606, ENCSR000EFJ, ENCSR000BTU, GSE67783, GSE101921, GSE135093, GSE206145-NatGen2015, GSE116344, GSE145327, GSE94872, GSE98367, GSE206145, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR000EDE, GSE68388, GSE83726, GSE50893
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Cell type: MDM, RH4, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, GM2255, IMR-90, DKO, H1-hESC, GM2588, SK-N-SH, Macrophage, HUES64, MCF-7, Hep-G2, HUVEC, HCAEC, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.744
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"9_Het": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, PGR, SMC1A, MYCN, CRY1, ZFX, STAG2, XBP1, DUX4, ZSCAN5A, FOXA1, SRF, CDK9, HOXB13, RELA, CDK6, RAD21, GRHL3, HIF1A, GATA3, GABPA, ZNF143, ARNTL, TRIM28, EZH2, KDM5B, OCA2, CTCF, BRD2, SPI1, AR, EGLN2, NOTCH3, SMC1, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): LTN1,LINC00113
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops