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Basic information

CohesinDB ID: CDBP00415909

Locus: chr21-28252418-28255220

Data sourse: GSE206145-NatGen2015, GSE165895

Cell type: Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 68%, "7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PAX7, FOSL1, PGR, FOXA2, NKX2-2, EZH2phosphoT487, FOXA1, HOXB13, SMARCC1, ERG, HOXC5, RELA, JUNB, RUNX2, SMARCA4, CHD7, LHX2, PBX4, GRHL3, ATF2, GATA3, STAT3, MAX, PBX3, NKX3-1, FOS, NR3C1, KLF4, CEBPB, TEAD1, PIAS1, HNF1B, GRHL2, PHOX2B, JUN, TCF12, CTCF, BAF155, EP300, BHLHE40, AR, IRF1, GATA2, ARID1A, FLI1, HSF1, BRD4, JUND, FOXP1, TEAD4, PDX1, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 22

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00415909