- Basic information
- CohesinDB ID: CDBP00415930
- Locus: chr21-28356817-28356967
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 96%,
"7_Enh": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, POU2F2, PGR, PPARG, FOXA2, MYCN, LDB1, TOP2A, SOX2, NME2, CHD2, XBP1, FOXF1, FOXA1, HOXB13, TWIST1, KDM1A, ERG, RELA, ZNF384, NEUROD1, MYC, CDK6, OSR2, CHD7, PRDM1, ARNT, GRHL3, ISL1, RAD21, OTX2, GATA3, PRDM9, TCF4, STAT3, PBX3, RCOR1, HAND2, MED1, TLE3, NR3C1, CEBPB, ETV1, NEUROG2, PIAS1, EZH2, SCRT2, PITX3, ZNF334, SETDB1, EBF3, PHOX2B, TCF12, USF1, SPI1, EP300, AR, GATA2, MAML3, ZNF605, BRD4, NOTCH3, MXI1, SCRT1, ZNF766, TEAD4, TBX2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops