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Basic information

CohesinDB ID: CDBP00415948

Locus: chr21-28421134-28422485

Data sourse: GSE206145, GSE206145-NatGen2015, GSE165895

Cell type: RPE, Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 69%, "7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, CHD8, PPARG, SIN3A, HNF1A, XBP1, SMAD3, GTF2B, DUX4, FOXA1, FOXF1, RELA, JUNB, RUNX2, MYC, EZH1, ZNF184, PRDM1, GRHL3, PBX4, HIF1A, ARNT, OTX2, GATA3, HMGB2, TAL1, STAT3, NRIP1, FOS, MED1, VDR, ARNTL, NR3C1, CEBPB, ZNF750, NR2F2, ETV1, EZH2, ESR1, HNF1B, ZNF334, SETDB1, EBF3, MYOD1, PHOX2B, JUN, TCF12, EP300, SP1, BHLHE40, AR, GATA6, PAX3-FOXO1, GATA2, BRD4, BCOR, TEAD4, MYF5, PDX1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00415948