- Basic information
- CohesinDB ID: CDBP00415956
- Locus: chr21-28454237-28456431
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE120943, GSE165895
-
Cell type: RPE, Fibroblast, Monocytes, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 67%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: MEF2B, SOX2, NME2, DUX4, FOXA1, ZNF205, CDK9, SMARCC1, RELA, MYC, RUNX2, GATA4, GRHL3, HIF1A, ZNF519, BATF, TAL1, MAX, MED1, ARNTL, NR3C1, CEBPB, LMO2, ELF3, CTCF, JUN, TCF12, SPI1, IRF1, EED, BRD4, JUND, CLOCK, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:25350000-25375000~~chr21:28425000-28450000,
chr21:26075000-26100000~~chr21:28425000-28450000,
chr21:26525000-26550000~~chr21:28425000-28450000,
chr21:26825000-26850000~~chr21:28425000-28450000,
chr21:27100000-27125000~~chr21:28425000-28450000,
chr21:27325000-27350000~~chr21:28425000-28450000,
chr21:27550000-27575000~~chr21:28425000-28450000,
chr21:27600000-27625000~~chr21:28425000-28450000,
chr21:27750000-27775000~~chr21:28425000-28450000,
chr21:28100000-28125000~~chr21:28425000-28450000,
chr21:28125000-28150000~~chr21:28425000-28450000,
chr21:28225000-28250000~~chr21:28425000-28450000,
chr21:28225000-28250000~~chr21:28450000-28475000,
chr21:28325000-28350000~~chr21:28425000-28450000,
chr21:28425000-28450000~~chr21:28625000-28650000,
chr21:28425000-28450000~~chr21:28700000-28725000,
chr21:28425000-28450000~~chr21:28725000-28750000,