- Basic information
- CohesinDB ID: CDBP00416010
- Locus: chr21-28699123-28700044
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045
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Cell type: MCF-7, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, SMARCE1, TP63, HDAC3, TEAD1, ELF1, ETV1, ZNF217, ESR1, OCA2, JUN, TCF12, BAF155, GATA6, TEAD4, TFAP2C, TOP2A, ZNF300, ERG, HNF4G, ONECUT1, MYC, RXRA, GABPA, STAT3, NKX3-1, RCOR1, NR3C1, ESRRA, CEBPB, CREB1, GRHL2, TRPS1, SPI1, EHF, GATA2, SIX2, RUNX1, CBX1, BCL6, ZFX, SMARCC1, CREBBP, GR, ARNT, SOX11, FOXM1, FOS, CDK8, MED1, MYB, PIAS1, BCL11A, REST, ARID1A, FOXP1, PPARG, FOXA2, MAFF, HOXB13, KDM1A, YY1, RELA, JUNB, AHR, HIF1A, GATA3, TLE3, KLF4, NR2F2, NR2F1, TCF7L2, NEUROG2, TP53, T, AR, EGLN2, HSF1, BRD4, JUND, CUX1, ZNF316
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops