- Basic information
- CohesinDB ID: CDBP00416033
- Locus: chr21-28776171-28776936
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Data sourse: ENCSR000EFJ, ENCSR000HPG, GSE206145-NatGen2015, GSE68388, GSE165895
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Cell type: Fibroblast, IMR-90, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZBTB24, FOXA2, CEBPA, TOP2A, HOXB13, SMARCC1, RELA, RUNX2, SMARCA4, RAD21, CHD7, GATA3, STAT3, MAX, FOS, GATA1, RCOR1, MED1, NR3C1, CEBPB, MAF, STAT5B, ESR1, MLL, CTCF, ZHX2, TCF12, BHLHE40, PAX3-FOXO1, GATA2, INTS13, BRD4, SMC3
- Target gene symbol (double-evidenced CRMs): LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000198862,
- Related loop:
chr21:25725000-25750000~~chr21:28750000-28775000,
chr21:26825000-26850000~~chr21:28750000-28775000,
chr21:26850000-26875000~~chr21:28750000-28775000,
chr21:26950000-26975000~~chr21:28750000-28775000,
chr21:28750000-28775000~~chr21:28900000-28925000,
chr21:28750000-28775000~~chr21:28925000-28950000,
chr21:28750000-28775000~~chr21:31075000-31100000,
chr21:28775000-28800000~~chr21:28925000-28950000,
chr21:28775000-28800000~~chr21:28950000-28975000,
chr21:28775000-28800000~~chr21:31075000-31100000,
chr21:28775000-28800000~~chr21:43275000-43300000,