- Basic information
- CohesinDB ID: CDBP00416043
- Locus: chr21-28801989-28802317
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Data sourse: ENCSR000HPG, GSE165895
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Cell type: IMR-90, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, FOS, ZNF35, NR3C1, CEBPB, GATA2, FOXA2, SOX2, BRD4, DUX4, JUND, FOXA1, ZNF189, JUN, MAFK, BHLHE40
- Target gene symbol (double-evidenced CRMs): LTN1,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000198862,
ENSG00000171189,
- Related loop:
chr21:28225000-28250000~~chr21:28800000-28825000,
chr21:28775000-28800000~~chr21:28925000-28950000,
chr21:28775000-28800000~~chr21:28950000-28975000,
chr21:28775000-28800000~~chr21:31075000-31100000,
chr21:28775000-28800000~~chr21:43275000-43300000,
chr21:28800000-28825000~~chr21:28900000-28925000,
chr21:28800000-28825000~~chr21:28925000-28950000,
chr21:28800000-28825000~~chr21:29675000-29700000,